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#livingmatter

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Jocelyn Etienne – research

Our article on the #mechanics of "active" entropic biopolymer networks [possibly including #actomyosin, this is debated experimentally] is now published in J Elas.

Compared to enthalpic models, we're able to go right from the #thermodynamics of an unbiased #molecularMotor activity (in the spirit of the model by #JacquesProst for #myosin) at the molecular scale to a network-scale model in a closed form.

And we derive a method for solving quite easily the (usually tough) #viscoelastic #liquid model that we obtain, using #deformationGradientDecomposition.

doi.org/10.1007/s10659-024-101
(I share a paywall-free link to my followers below, but it's also on arXiv: arxiv.org/abs/2405.07287 and on my webpage liphy-annuaire.univ-grenoble-a)

The microstructure is made of entropic chains which form a network but can transiently unbind, relax and rebind. Together with affine deformations in the velocity graident, this gives a viscoelastic liquid rheology. What we add is the flux $j_a$ created by molecular motors.
Deformation gradient decomposition in action: finding the dynamics of a tangentially contractile sphere bound elastically to a fixed sphere.
#cytoskeleton#cell#tissue
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