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#hippocampus

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“The posterior hippocampi of taxi drivers were significantly larger relative to those of control subjects,” she wrote in Proceedings of the National Academy of Sciences. And the size, she found, correlated with the length of a cabby’s career: The longer the cabby had driven, the bigger the hippocampus.
#neurobiology #science #memory #brainscience #hippocampus #physiology #biology
nytimes.com/2025/02/14/science

Eleanor Maguire in an undated photo. “She changed our understanding of memory,” said Chris Frith, an emeritus professor of neuropsychology at University College London.
The New York Times · Eleanor Maguire, Memory Expert Who Studied London Cabbies, Dies at 54By Michael S. Rosenwald

"In mice, here we reveal a non-pyramidal excitatory neuron type — the “ovoid” neuron — that is spatially adjacent to subiculum pyramidal cells but differs in gene expression, electrophysiology, morphology, and connectivity. Functionally, novel object encounters drive sustained ovoid neuron activity, whereas familiar objects fail to drive activity even months after single-trial learning."

nature.com/articles/s41467-025

NatureAtypical hippocampal excitatory neurons express and govern object memory - Nature CommunicationsPyramidal cells are classically thought to comprise the excitatory output of the subiculum. Here, the authors show the existence of “ovoid cells”, excitatory subiculum neurons with specialized gene expression, morphology, projections, and function.

@johnwidloski and I are co-organizing a symposium on #HippocampalReplay at the #EBBS25 in Bordeaux!

Our goal: From the state of the art in awake replay models & existing data, determine the next big questions and most informative future experiments to finally figure out what is awake replay for!

Our speakers:

  • John Widloski
  • Lisa Genzel
  • Jacob Bakermans
  • Elisa Massi

Meeting dates: 28 June to 1 July 2025 (our symposium is on the last day

Programme: ebbs2025.azuleon.org/programme

The abstract submission deadline for posters (and early bird registration) is on 31 March 2025 - I hope to see you there!

ebbs2025.azuleon.orgEBBS 2025 :: ProgrammeThe website of the 51st EBBS Meeting :: EBBS 2025

𝓑𝓵𝓾𝓮𝓼 𝓭𝓮 𝓵’𝓱𝓲𝓹𝓹𝓸𝓬𝓪𝓶𝓹𝓮

« Je suis votre fiction, votre image océane
L’hippocampe en rut depuis quatre cent mille siècles
Debout, d’une seule nageoire, j’avance depuis l’éocène
Auguste figure du poète, éloge de la lenteur. »
Extrait d’un texte de Jean Royer, juin 2006

© illustration : Cécile Ollichon - by the ink