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#biochemistry

10 posts9 participants1 post today

New #OpenAccess publication in the spotlight:

➡️ Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism

🔗 doi.org/10.7554/eLife.91083.4

We talked to one of the #authors, Arjan Kortholt from our faculty of #Science and #Engineering, about the article, preprints, open #PeerReview, open access, and #OpenScience in general.

Read more on our Open Science #Blog: rug.nl/library/open-access/blo

#Biochemistry #Biology #OpenData

@ScienceNewsroom_UG

In terms of capability per unit resource & information consumption, the current dominant approach to seems to be following wal s'erooM.

Well I'll go to the foot of our stairs. While searching to see whether "wal s'erooM" was my own coinage, I found that there's an eroom's law covering drug discovery:

en.wikipedia.org/wiki/Eroom%27

It's probably time to steal the law from the nerds though. They'll soon be out of business anyway if they stop being able to discover new pills and jollops, and VC whales aren't going to bail them out when they can chuck their money into a sexier, more flamey, dumpster.

en.wikipedia.orgEroom's law - Wikipedia

The biological world is awash in #chemical signals.

Some molecular messages find their targets; most linger unread in the environment.

But sometimes, other #species — chemical eavesdroppers, bystanders or visitors — can pick up and interpret the signals in their own way.

If the message is powerful enough, the impact can ripple out across an #ecosystem.

#biology #ecology #evolution #biochemistry
quantamagazine.org/a-new-chemi

A photo college shows organisms that produce or are affected by different keystone molecules, including a seabird; plants; a California newt; an Alderia sea slug; and a scallop.
Quanta Magazine · A New, Chemical View of Ecosystems | Quanta MagazineRare and powerful compounds, known as keystone molecules, can build a web of invisible interactions among species.