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#immunology

6 posts3 participants0 posts today
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datum (n=1)
AJ's got a new blog post! Some highlights:
"a Nature Immunology study from January 2024 "Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2" reveals further harm through T cell dysregulation in long COVID patients. The research identified increased frequencies of exhausted SARS-CoV-2-specific CD8+ T cells, alongside CD4+ T cells primed for inflammation, and a lack of coordination between T and B cell responses."
"a paper in JCI insight showing T cell exhaustion to other infections following a covid infection"
"a Nature Immunology study from January 2022 "Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection" shows that COVID-19 leads to a prolonged reduction in naive T cells (both CD4+ and CD8+) in individuals with long COVID, persisting up to eight months post-infection."
"Such a long-term impact on the naive T cell pool is not a standard feature of recovery from other acute viral infections like influenza, [...] This effect may not completely persist, however, what it represents is sloughing of the T cells."
A study published in Immunity found "Even after vaccination, those with a history of COVID-19 showed weaker and less functional CD8+ T cell responses, a phenomenon likened to the immune damage seen in chronic viral infections like hepatitis C or HIV. This attenuation indicates that SARS-CoV-2 inflicts a lasting impairment on CD8+ T cell effector function"
from https://www.easychair.info/p/5-years-later-covid-still-harms-t #AirborneAware #CovidCompetent #COVIDIsNotOver #COVID #COVID19 #SARSCoV2 #immunology #LongCOVID
Easy Chair · 5 Years later, Covid still Harms T cellsBy Anthony J Leonardi, MBBS, PhD
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Brittany Trang

A double-PhD byline from STAT's immunology expert Jonathan Wosen and ...me:

What if we could read your diseases from your immune cells? A new machine learning technique brings such a diagnostic, especially aimed at autoimmune disease, closer to reality:

More @STAT
statnews.com/2025/02/20/machin

STAT · A newly developed machine learning-based test could diagnose autoimmune diseases fasterA new machine learning based test diagnosed Covid-19, HIV, flu, lupus, and Type-1 diabetes by studying immune cells.
#health#healthcare#medicine
Public
airr_community

We're thrilled to announce the upcoming AIRR-C Seminar Series on March 15, 2023, at 3 PM EST!

Join us for an insightful session with Steven E. Bosinger, "A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques" and Maria F. Abbate, "Computational detection of antigen specific BCRs for antibody discovery.".

#AIRRC #Immunology #AntibodyResearch #SeminarSeries

antibodysociety.org/the-airr-c

The Antibody SocietyAIRR Community Seminar Series - The Antibody SocietyJoin the AIRR Community for a 90 minute “lab-style” virtual seminar. Each month an established and an early career scientist will discuss their AIRR-seq related research. Seminar time will be 16:00 – 17:30 Central European Time (CET), typically on the 4th Thursday of the month. Most talks will be recorded and posted on the AIRR […]
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